Publications
McDaniel, S. L., Hepperla, A., Huang, Jie, Kulkarni, V. G., Davis, I. J. & Strahl, B. D. (2017) H3K36 Methylation Regulates Nutrient Stress Response in Saccharomyces cerevisiae by Enforcing Transcriptional Fidelity. In Press at Cell Reports.
McDaniel, S. L. & Strahl, B. D. (2017) Shaping the Cellular Landscape with Set2/SETD2 methylation. Cellular & Molecular Life Sciences. doi: 10.1007/s00018-017-2517-x.
Khan, A.*, Bridgers, J. B.* & Strahl, B. D. (2017) Expanding the reader landscape of histone acylation. Structure. 25:571-573.
Meers, M., P., Henriques, T., Lavender, C. A., McKay, D. J., Strahl, B. D., Duronio, R. J., Adelman, K. & Matera, A. G. (2017) Histone replacement decouples H4 acetylation from cryptic transcription in H3K6 mutants and reveals a post-transcriptional mechanism for maintaining transcriptome fidelity in animals. ELife. pii: e23249. doi: 10.7554/eLife.23249
Shanle, E. K.*, Shinsky, A. A.*, Bridgers, J. B., Bae, N., Sagum, C., Krajewski, K., Rothbart, S. B., Bedford, M. T.* & Strahl, B. D.* (2017) Histone peptide microarray screen of chromo and Tudor domains defines new histone lysine methylation interactions. Epigenetics & Chromatin. 10:12. doi: 10.1186/s13072-017-0117-5.
Savitsky, P., Krojer, T., Fujisawa, T., Lambert, J.P., Picaud, S., Wang, C.Y., Shanle, E. K., Krajewski, K., Friedrichsen, H., Kanapin, A., Goding, C., Schapira, M., Samsonova, A., Strahl, B. D., Gingras, A.C. & Filippakopoulos, P. (2016) Multivalent histone and DNA engagement by a PHD/BRD/PWWP triple reader cassette recruits ZMYND8 to K14ac-rich chromatin. Cell Reports. 17:2724-2737.
Charpentier, T. H., Waldo, G. L., Lowery-Gionta, E. G., Krajewski, K., Strahl, B. D., Kash, T. L., Harden, K. & Sondek, J. (2016) Potent and selective peptide-based inhibition of Gαq. Journal of Biological Chemistry. 18:1127-1138.
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Strikoudis, A., Lazaris, C., Trimarchi, T., Galvao Neto, A. L., Yang, Y., Ntziachristos, P., Rothbart, S. D., Buckley, S., Dolgalev, I., Stadtfeld, M., Strahl, B. D., Dynlacht, B. D., Tsirigos, A & Aifantis, I. Regulation of transcriptional elongation in pluripotency and Cell differentiation by the PHD-finger protein Phf5a. Nature Cell Biology. 18:1127-1138.
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Andrews, F. H., Tong, Q., Sullivan, K. D., Cornett, E., Zhang, Y., Muzaffar, A., Ahn, J., Strahl, B. D., Costello, J. C., Espinosa, J. M., Rothbart, S., B. & Kutateladze, T. G. (2016) Multivalent chromatin engagement and inter-domain crosstalk regulate MORC3 ATPase. Cell Reports.16:3195-31207.
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Hacker, K. E.*, Fahey, C. C.*, Shinsky, S. A.*, Chiang, Y.-C. J.*, DiFiore, J. V.*, Jha, D. K., Vo, A. H., Shavit, J. A. Davis, I, J., Strahl, B. D.* & Rathmell, W. K.* (2016) Structure/Function Analysis of Recurrent Mutations in SETD2 Reveals a Critical and Conserved Role for a SET Domain Residue in Maintaining Protein Stability and H3K36 Trimethylation. Journal of Biological Chemistry. 291: 21283-21295.
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Chen, H., Workman, J. J., Strahl, B. D. & Laribee, R. N. (2016) Histone H3 and TORC1 Prevent Organelle Dysfunction and Cell Death by Promoting Nuclear Retention of HMGB Proteins. Epigenetics & Chromatin. 9:34.
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Harrison, J. S., Cornett, E. M., Goldfarb, D., DaRosa, P. A., Li, Z. M., Yan, F., Dickson, B. M., Guo, A. H., Cantu, D. V., Kaustov, L., Brown, P. J., Arrowsmith, C. H., Klevit, R. E., Erie, D. A., Major, M. B., Krajewski, K., Kuhlman, B., Strahl, B. D. & Rothbart, S. B. (2016) Hemi-methylated DNA regulates DNA methylation inheritance through allosteric control of H3 ubiquitylation by UHRF1. ELife. pii: e17101. doi: 10.7554/eLife.17101.
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Penke, T. J. R., McKay, D. J., Strahl, B. D., Matera, A. G & Duronio, R. J. (2016) Direct interrogation of the role of H3K9 in metazoan heterochromatin function. Genes & Development. 30:1866-1880.
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Andrews, F. H., Strahl, B. D. & Kutateladze, T. G. (2016) Insights into newly discovered marks and readers of epigenetic information. Nature Chemical Biology. 12:662-668.
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Cornett, E. M., Dickson, B. M., Vaughan, R. M., Trievel, R. C., Strahl, B. D. & Rothbart, S. B. (2016) Substrate specificity profiling of histone-modifying enzymes by peptide microarray. Methods in Enzymology. 574:3-29.
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McDaniel, S. L., Fligor, J. E., Chun, R., Cui, H., Bridgers, J. B., DiFiore, J. V., Guo, A. H., Li, B. & Strahl, B. D. (2016) Combinatorial Histone Readout by the Dual Plant Homeodomain (PHD) Fingers of Rco1 Mediates Rpd3S Chromatin Recruitment and the Maintenance of Transcriptional Fidelity. J of Biol Chemistry. 291:14796-14802.
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Bedard, L. G., Dronamraju, R., Kerschner, J.L., Hunter, G.O., Axley, E.D., Boyd, A.K., Strahl, B.D. & Mosley, A.L. (2016) Quantitative analysis of dynamic protein interactions during transcription reveals a role for casein kinase II in PAF complex phosphorylation and regulation of H2B monoubiquitylation. J of Biol Chemistry. 291:13410-13420.
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Andrews, F. H.*, Shinsky, A. S.*, Shanle, E. K., Bridgers, J. B., Gest, A., Tsun, I. K., Krajewski, K., Shi, X., Strahl, B. D.* & Kutateladze, T. G.* (2016) The Taf14 YEATS domain is a reader of histone crotonylation. Nature Chemical Biology. 12:396-398.
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Yumerefendi, H., Lerner, A. M., Zimmerman, S. P., Hahn, K., Bear, J. E., Strahl, B. D. & Kuhlman, B. (2016) Light-induced nuclear export reveals rapid dynamics of epigenetic marks. Nature Chemical Biology. 12:399-401.
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Gatchalian, J., Mora, C., Shinsky, S. A., Ospina, R. R., Mansilla, A. L., Klein, B. J., Andrews, F. H., Strahl, B. D., van Wely, K. H. M. & Kutateladze, T. G. (2016) Chromatin condensation and recruitment of PHD fingers to histone H3K4me3 are mutually exclusive. Nucleic Acids Research. Mar 25. pii: gkw193.
Sorenson, M. R., Jha, D. K., Ucles, S., Flood, D., Strahl, B. D., Stevens, S. W. & Kress, T. L. (2016) Histone H3K36 methylation regulates pre-mRNA splicing in Saccharomyces cerevisiae. RNA Biology. 13:412-426.
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Hattori, T., Lai, D., Dementieva, I. S., Montano, S. P., Zheng, Y., Akin, L., Swift, K., M., Grzybowski, A. T., Koide, A., Krajewski, K., Strahl, B. D., Kelleher, N. L., Ruthenburg, A. J. & Koide, S. (2016) Antigen clasping by two antigen-binding sites of an exceptionally specific antibody for histone methylation. Proc Natl Acad Sci USA. 113:2092-2097.
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Andrews, F. H.*, Shanle, E. K.*, Strahl, B. D.* & Kutateladze, T. G.* (2016) The essential role of acetyllysine binding by the YEATS domain in transcriptional regulation. Transcription. 7:14-20.
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Andrews, F. H., Gatchalian, J., Krajewski, K., Strahl, B. D. & Kutateladze, T. G. (2016) Regulation of methyllysine readers through phosphorylation. ACS Chem Biol. 7:14-20.
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Shanle, E. K., Tsun, I. K. & Strahl, B. D. (2016) A course-based undergraduate research experience investigating p300 bromodomain mutations. Biochemistry and Molecular Biology Education. 44:68-74.
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Cliffe, A. R., Vogel, J. L., Arbuckle, J. H., Geden, M. J., Rothbart, S. B., Cusack, C. L., Strahl, B. D., Kristie, T. M., Deshmukh, M. A (2015) Neuronal stress pathway mediating a histone Methyl/Phospho switch is required for Herpes Simplex Virus Reactivation. Cell Host and Microbe. 18:649-658.
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Chen, S., Ze, Y., Wilkinson, A., Deshpande, A. J., Krajewski, K., Strahl, B. D., Armstrong, S. A., Patel, D., J. & Gozani, O. (2015) The PZP domain of AF10 senses unmodified H3K27 to regulate DOT1L-mediated methylation of H3K79. Molecular Cell. 60:319-327.
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Shanle, E. K, Andrews, F. H., Meriesh, H., McDaniel, S. L., Dronamraiu, R., DiFiore J., Jha, D., Wozniak, G. G., Bridgers, J., Kerschner, J. L., MartÃn, G. M., Morrison A. J., Krajewski, K., Kutateladze, T.* & Strahl, B. D.* (2015) Association of Taf14 with acetylated histone H3 directs gene transcription and the DNA damage response. Genes & Development. 29:1789-1794.
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Simon, J. M., Parker, J. S., Liu, F., Rothbart, S. B., Ait-Si-Ali, S., Strahl, B. D., Jin, j., Davis, I. J., Mosley, A. L. & Pattenden, P. G. (2015) A role for Widely Interspaced Zinc finger (WIZ) in retention of the G9a methyltransferase on chromatin. Journal of Biological Chemistry. 290:26088-26102.
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Zhang, Z.-M., Rothbart, S. B., Allison, D., Cai, Q., Harrison, J. S., Li, L., Wang, Y., Strahl B. D., Wang, G. G., Song, J. (2015) An allosteric interaction links USP7 to deubiquitination and chromatin targeting of UHRF1. Cell Reports. 12:1400-1406.
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Ali, F. A., Daze, K. D., Rothbart, S. B., Strongin, D. E., Rincon-Arano, H., Allen, H. F., Li, J., Groudine, M., Strahl, B. D., Hof, F. & Kutateladze, T. G. (2015) Molecular Insights into Inhibition of the Methylated Histone-Plant Homeodomain Complexes by Calixarenes. J of Biol Chemistry. 290:22919-22930.
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Rothbart, S. B., Dickson, B. M., Raab, J. R., Grzybowski, A. T., Krajewski, K., Guo, A. H., Shanle, E. K., Josefowicz, S. Z., Fuchs, S. M., Allis, C. D., Magnuson, T. R., Ruthenburg, A. J. & Strahl, B. D. (2015) An interactive database for the assessment of histone antibody specificity. Molecular Cell. 59:502-511.
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Wang, L., Xie, L., Ramachandran, S., Lee, Y., Yan, Z., Zhou, L., Krajewski, K., Liu, F., Zhu, C., Chen, D., Strahl, B. D., Jin, J., Dokholyan, N. V. & Chen, X. (2015) Non-canonical bromodomain within DNA-PKcs promotes DNA damage response and radioresistance through recognizing an IR-induced acetyl-lysine on H2AX. Chemistry & Biology. 22:1-13.
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Rothbart, S. B., Dickson, B. M. & Strahl, B. D. (2015) From Histones to Ribosomes: A Chromatin Regulator Tangoes with Translation. Cancer Discovery. 5:228-30.
Perfetti, M. T., Baughman, B. M., Dickson, B. D. Mu, Y., Cui, G., Mader, P., Dong, A., Norris, J. L., Rothbart, S. B., Strahl, B. D., Brown, P. J., Janzen, W. P., Arrowsmith, C. H., Mer, G., McBride, K., James, L., & Frye, S. V. (2015) Identification of a Fragment-like Small Molecule Ligand for the Methyl-lysine Binding Protein, 53BP1. ACS Chemical Biology. 10:1072-1081.
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McKay, D. J., Klusza, S., Penke, T. J., R., Meers, M. P., Curry, K. P., McDaniel, S. L., Malek, P. Y., Cooper, S. W., Tatomer, D., C., Lieb, J. D., Strahl, B. D., Duronio, R. J. & Matera, A. G. (2015) Interrogating the function of metazoan histones using engineered gene clusters. Developmental Cell. 32:373-86.
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Tong, Q., Mazur, S., J., Rincon-Arona, H., Rothbart, S. B., Kuznetsov, D. M., Cui, G., Liu, W. H., Gete, Y., Klein, B. J., Jenkins, L., Mer, G., Kutatelasze, A., G., Strahl, B. D., Groudine, M., G., Appella, E. & Kutateladze, T., G. An acetyl-methyl switch drives a conformational change in p53. Structure. 23:322-31.
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Tong, Q., Cui, G., Botuyan, M. V., Rothbart, S. B., Hayashi, R., Musselman, C. A., Appella, E., Strahl, B. D., Mer, G. & Kutateladze, T. G. (2015) Structural plasticity of methyllysine recognition by the tandem Tudor domain of 53BP1. Structure. 23:312-21.
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Dumesic, PA, Homer, CM, Moresco, JJ, Pack, LR., Shanle, EK., Coyle, SM., Strahl, BD, Fujimori, DG, Yates, J. R. & Madhani, HD. (2015) Product binding enforces the genomic specificity of a yeast polycomb repressive complex. Cell. 160:204-218.
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Gilbert, T. M.*, McDaniel, S. L.*, Byrum., S. D., Cades, J. A., Dancy, B. C. Y, Wade, H., Tackett, A. J., Strahl, B. D.* & Taverna, S. D.* (2014) A PWWP domain-containing protein targets the NuA3 acetyltransferase complex via H3 lysine 36 trimethylation to coordinate transcriptional elongation at coding regions. Mol Cell Proteo. 13:2883-2895.
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Jha, DK & Strahl, BD (2014) SET-ing stage for DNA Repair. Nat Str Mol Bio 5:655-657
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Wozniak, G. G. & Strahl, B. D. (2014) Catalysis-dependent stabilization of Bre1 fine-tunes histone H2B ubiquitylation to regulate gene transcription. Genes & Dev 28:1647-1652.
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Shanle, E. K., Rothbart, S. B. & Strahl, B. D. (2014) Chromatin biochemistry enters the next generation of code ‘seq-ing’ Nature Methods. 11:799-800.
Jha, D. K. & Strahl, B. D. (2014) H3K36 methylation regulates chromatin remodeling and checkpoint activation after DSB. Nature Commun. 5:3965.
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Greer, E. L., Beese-Sims, S. E., Spadafora, R., Rothbart, S. B., Badeaux, A. I., Strahl, B. D., Colaiácovo, M. P. & Shi, Y. (2014) histone methylation network regulates transgenerational epigenetic memory in C. elegans. Cell Reports. 7:113-26.
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Wozniak, G. G. & Strahl, B. D. (2014) Hitting the 'Mark': Interpreting Lysine Methylation in the Context of Active Transcription. BBA - Gene Regulatory Mechanisms.
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Rothbart S. B. & Strahl, B. D. (2014) Interpreting the language of histone and DNA modifications. BBA - Gene Regulatory Mechanisms.
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Kim, H.-S., Mukhopadhyay, R., Rothbart, S. B., Silva, A. C., Vanoosthuyse, V., Radovani, E., Kislinger, T., Roguev, A., Ryan, C. J., Xu, J., Jahari, H., Hardwick, K., G., Greenblatt, J. F., Krogan, N. J., Fillingham, J., S., Strahl, B. D., Bouhassira, E., E., Edelmann, W. & Keogh, M.-C. (2014) Identification of a novel Bromodomain/Casein Kinase II/TAF-containing complex as a regulator of mitotic condensin function. Cell Reports. 6:1-14
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Klein, B. J., Piao, L., Xi, Yuanxin, Rincon-Arano, H., ROthbart, S. B., Larson, C., Wen, H., Zheng, X., Cortazar, M., Pena, P. V., Mangan, A., Bentley, D. L., Strahl, B. D., Groudine, M., Li, W., Shi, X., Kutateladze, T. G. (2014) The histone-H3K4-specific demethylase KDM5B binds to its substrate and product through distinct PHD dingers. Cell Reports. 6:1-11.
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Dronamraju, R. & Strahl B. D. (2014) A feed forward circuit comprising Spt6, Ctk1 and PAF regulates Pol II CTD phosphorylation and transcription elongation. Nucleic Acids Research. 42(2):870-881.
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Hattori, T., Taft, J., Swift, K., Luo, H., Witt, H., Slattery, M., Koide, A., Ruthenburg, A. J., Krajewski, K., Strahl, B. D., White, K. P., Farnham, P. J., Zhao, Y., Koide, S. (2013) Recombinant antibodies to histone posttranslational modifications. Nature Methods. 10:992-995.
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McDaniel S. L. & Strahl, B. D. (2013) Stress-Free with Rpd3: A unique chromatin complex mediates the response to oxidative stress. Mol Cell Biol. 33:3726-3727.
Kinkelin, K., Wozniak, G. G., Rothbart, S. B., Lidschreiber, M., Strahl B. D. & Cramer, P. Structures of RNA polymerase II complexes with Bye1, a chromatin-binding PHF3/DIDO1 homologue. (2013) Proc Natl Acad Sci USA. 110:15277-15282.
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Gatchalian, J., Fütterer, A., Rothbart, S. B.,Tong, Q., Rincon-Arano, H., Sánchez de Diego, A. Groudine, M., Strahl, B. D., Martínez-AC, van Wely, HMK. & Kutateladze, T. G. Dido3 PHD modulates Cell differentiation and division. (2013) Cell Rep. 11:148-158.
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Ali, M., Rincon-Arano, H., Zhao., W., Rothbart, S. B., Tong, Q., Parkhurst, S., Strahl B. D., Deng, L.-W., Groudine, M., Kutateladze, T. G. (2013) Molecular basis for chromatin binding and regulation of MLL5. Proc Natl Acad Sci USA. 110:11296-11301.
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Rothbart, S. B., Dickson, B. M., Ong, M. S., Krajewski, K., Houliston, S., Kireev, D. B., Arrowsmith, C. H. & Strahl, B. D. (2013) Multivalent histone engagement by the linked tandem Tudor and PHD domains of UHRF1 is required for the epigenetic inheritance of DNA methylation. Genes & Development. 27:1288-1298.
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Law, J. A., Du, J., Hale, C. J., Feng, S., Krajewski, K., Strahl, B. D., Patel, D. J. & Jacobsen, S. E. (2013) SHH1 recruits RNA Polymerase-IV to RNA-directed DNA methylation targets. Nature. 498:385-389.
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Cai, L, Rothbart, SB, Lu, R, Xu, B, Tripathy, A, Chen, WY, Zheng, D, Patel, DJ, Allis, CD, Strahl, BD, Song, J, Wang, GG (2013) An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting. Mol Cell. 49:571-582.
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Ali, M., Yan, K., Lalonde, M.-E., Degerny, C., Rothbart, S. B., Strahl, B. D., Cote, J., Yang, X-.J. & Kutateladze, T., G. (2012) Tandem PHD fingers of MORF/MOZ acetyltransferases display selectivity for acetylated histone H3 and are required for the association with chromatin. J. Mol. Biol. 424:328-288.
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Nishikori, S., Fuchs, S. M., Yasui, N., Wojcik, J., Koide, A., Strahl, B. D. & Koide, S. A (2012) quantitative and sensitive method for characterizing anti-histone antibodies. J. Mol. Biol. 424:391-399.
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Rizzardi, L. F., Dorn, E. E. Strahl B. D. & Cook J. G. (2012) H3K4 di-methylation promotes DNA replication origin function in Saccharomyces cerevisiae. Genetics 192:371-384.
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Rothbart, S. B., Krajewski, K., Nady, N., Tempel, W., Xue, S., Badeaux, A. I., Barsyty-Lovejoy, D., Martinez, J. Y., Bedford, M. T., Fuchs, S. M., Arrowsmith, C. H. & Strahl, B. D. (2012) Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation. Nature Structural & Molecular Biology. 19:1155-1162. News & Views article highlighting this work was featured in Epigenomics (2012) 4:597-599
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Bánfai, B., Jia, H., Khatun, J., Wood, E., Risk, B., Gundling, W., Kundaje, A., Gunawardena, H. P., Yu, Y., Xie, L., Krajewski, K., Strahl, B. D., Chen, X., Bickel, P. J., Giddings, M. C., Brown, J. B. & Lipovich, L. (2012) Long non-coding RNAs are rarely translated. Genome Research. 22:1646-1657.
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Stolzenburg, S., Rots, M. G., Beltran, A. S., Rivenbark, A. G., Yuan, X., Strahl, B. D. & Blancafort, P. (2012) Targeted silencing of the oncogene transcription factor SOX2 in breast cancer. Nucleic Acid Res. 40:6725-6740.
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Rothbart, S. B., Krajewski, K., Strahl B. D., Fuchs, S. M. (2012) Peptide microarrays to interrogate the histone code. Methods Enzymol. 512:107-135.
Rothbart, S. B., Lin, S., Britton, L.-M., Krajewski, K., Keogh, M.-C., Garcia, B. & Strahl, B. D. (2012) Poly-acetylated chromatin sigNatures are preferred epitopes for site-specific histone H4 acetyl antibodies. Scientific Reports. 2:489.
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Rivenbark, AG, Stolzenburg, S, Yuan, X, Strahl, BD & Blancafort, P. (2012) Epigenetic reprogramming of Cancer Cells by targeted DNA methylation. Epigenetics. 7:1-11.
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Fuchs, SM, Kizer, KO, Braberg, H, Krogan, N. & Strahl, BD. (2012) RNA polymerase II CTD phosphorylation regulates protein stability of the Set2 methyltransferase and histone H3 di- and trimethylation at lysine 36. J Biol Chem. 287:3249-3256.
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Fuchs, S. M. & Strahl, B. D. (2011) Antibody recognition of histone post-translational modifications: emerging issues and future prospects. Epigenomics. 3:247-249.
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Kerr, S. C., Azzouz, N., Fuchs, F. S., Collart, M. A., Strahl, B. D., Corbett, A. H. & Laribee, R. N. (2011) The CCR4-NOT complex physically and functionally interacts with the mRNA export pathway. PLoS ONE. 6:e18302.
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Gardner, K. E., Allis, C. D. & Strahl, B. D. (2011) OPERating ON chromatin, a colorful language where context matters. J. Mol. Biol. 409:36-46.
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Gardner K. E., Zhou, L., Parra, M. A., Chen, X. & Strahl, B. D. (2011) Identification of lysine 37 of histone H2B as a novel site of methylation. PLoS ONE. 6:e16244.
Ramachandran, S., Vogel, L., Strahl, B. D.* & Dokholyan, N. V.* (2011) Thermodynamic stability of protein-protein interaction is a necessary but not sufficient driving force for evolutionary conservation. PLoS Comput Biol. 7:e1001042.
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Fuchs SM, Krajewski K, Miller V, Baker R & Strahl, BD (2011) Influence of combinatorial histone modifications on antibody & effector protein recognition. Cur Biol. 11:53-58.
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Nakanishi, S., Lee, J. S., Gardner, K. E., Gardner, J. M., Takahashi, Y-H., Chandrasekharan, M. B., Sun, Z-W., Osley, M. A., Strahl, B. D., Jaspersen, S. L. & Shilatifard, A. (2009) Histone H2BK123 monoubiquitination is the critical determinant for H3K4 and H3K79 trimethylation by COMPASS and Dot1. J of Cell Biol. 186:371-377.
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Lickwar, C.*, Rao, B.*, Shabalin, A., Nobel, A., Strahl, B. D. & Lieb, J. D. (2009) The Set2/Rpd3S pathway suppresses cryptic transcription without regard to gene length or transcription frequency PLoS ONE. 4:e4886
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Fuchs, S. M., Laribee, R. N. & Strahl, B. D. (2009) Protein modifications in transcription elongation. BBA - Gene Regulatory Mechanisms. 1789:26-36.
Henikoff, S., Strahl, B. D. & Warburton P. E. (2008) Epigenomics: a roadmap to chromatin. Science. 322:853.
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Youdell, M. J.*, Kizer, O. K.*, Kisseleva-Romanova, E. Fuchs, S. M., Duro, E., Korn, K., Strahl, B. D. & Mellor, J. (2008) Spt6 controls methylation of lysine 36 on histone H3 to stabilize transcribed chromatin. Mol Cell Biol. 16:4915-4926.
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Merker, J. D., Dominska, M., Greenwell, P. W., Rinella, E., Bouck, D. C., Shibata, Y., Strahl, B. D., Mieczkowski, P. & Petes, T. D. (2008) The histone methylase Set2p and the histone deacetylase Rpd3p repress meiotic recombination at the HIS4 meiotic recombination hotspot in Saccharomyces cerevisiae. DNA Repair 7:1298-308.
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Rivenbark, A. G. & Strahl B. D. (2007) Unlocking cell fate. Science 318:403-404.
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Wyce A, Xiao T, Whelan KA, Kosman C, Walter W, Eick D, Hughes TR, Krogan NJ, Strahl BD & Berger SL (2007) H2B ubiquitylation acts as a barrier to Ctk1 nucleosomal recruitment prior to removal by Ubp8 w/n SAGA-related complex. Mol Cell. 27:275-88.
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Laribee, R. N., Shibata, Y., Mersman, D. P., Roguev, A., Collins, S. R., Kemmeren, P., Weissman, J. S., Briggs, S. D., Krogan, N. J.* & Strahl, B. D.* (2007). The CCR4/NOT complex associates with the proteasome and regulates histone methylation. Proc Natl Acad Sci USA 104:5836-5841.
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Laribee, R. N., Fuchs, S. M. & Strahl B. D. (2007) H2B ubiquitylation in transcriptional control: a FACT finding mission. Genes & Dev. 21:737-743.
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Morris, S. A., Rao, B., Garcia, B. A., Hake, S. B., Diaz, R. L., Shabanowitz, J., Hunt, D. F., Allis, C. D., Lieb, J. D. & Strahl, B. D. (2007) Identification of histone H3 lysine 36 acetylation as a highly conserved modification. J Biol Chem. 282:7632-7640.
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Garcia, B. A., Hake, S. B., Diaz, R. L., Kauer, M., Morris, S. A., Recht, J., Shabanowitz, J., Mishra, N., Strahl, B. D., Allis, C. D. & Hunt, D. F. (2007) Organismal differences in post-translational modification in histones H3 and H4. J Biol Chem. 282:7641-7655.
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Xiao, T, Shibata, Y, Rao, B, Laribee, RN, Krogan, JN, Greenblatt, JF, Rourke, RO, Buck, MJ, Lieb, JD & Strahl, BD (2007) The RNA Pol II kinase Ctk1 regulates positioning of a 5' histone methylation boundary along genes. M Cell Biol. 27:721-731.
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Kizer, O. K., Xiao, T. & Strahl, B. D. (2006) Accelerated nuclei preparation and methods for the analysis of histone modifications in yeast. Methods 40:296-302.
Biswas, D., Duttu-Biswas, R., Mitra, D., Shibata, Y., Strahl, B. D., Formosa, T., Stillman, D. J. (2006) Opposing roles for Set2 and yFACT in regulating TBP binding at promoters. EMBO J. 25:4479-4489.
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Tripic, T., Edmondson, D., Davie, J, Strahl, B. D. & Dent, S.R. (2006) The Set2 methyltransferase associates with Ssn6 yet Tup1-Ssn6 repression is independent of histone methylation. Biochem Biophys Res Comm. 339:905-14.
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Vojnic, E., Simon, B., Strahl, B. D., Sattler, M. & Cramer, P. (2006) Structure and CTD binding of the Set2 SRI domain that couples histone H3 K36 methylation to transcription. J Biol Chem. 281:13-15.
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Keogh, M.-C., Kurdistani, S. K., Morris, S. A., Ahn, S. H., Collins, S. R., Podolny, V., Chin, K., Punna, T., Thompson, N. J., Boone, C., Emili, A., Weissman, J. S., Hughes, T. R., Strahl, B. D., Grunstein, M., Greenblatt, J. F., Buratowski, S., & Krogan, N. J. (2005) Co-transcriptional Set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex. Cell 123:593-605.
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Rao, B., Shibata, Y., Strahl, B. D. & Lieb, J. D. (2005) Dimethylation of Histone H3 at Lysine 36 Occurs Co-transcriptionally to Demarcate Regulatory and Non-Regulatory Chromatin Genome-wide. Mol Cell Biol. 25:9447-9459.
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Laribee, R. N., Krogan, J. N., Xiao, T., Shibata, Y., Hughes, T. R., Greenblatt, J. F. & Strahl, B. D. (2005) BUR kinase selectively regulates H3 K4 trimethylation and H2B ubiquitylation through recruitment of the PAF elongation complex. Current Bio. 15:1487-1493.
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Morris, S. A., Shibata, Y., Noma, K.-I., Tsukamoto, Y., Warren, E., Temple, B., Grewal, S. I. S. & Strahl, B. D. (2005) Histone H3 K36 methylation is associated with transcription elongation in Schizosaccharomyces pombe. Eukaryot Cell. 4:1446-1454.
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Adhvaryu, K. K., Morris, S., Strahl, B. D. & Selker, E.U. (2005) Methylation of histone H3 lysine 36 is required for normal development in Neurospora crassa. Eukaryot Cell. 4:1455-1464.
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Kizer, O. K., Phatnani, H. P., Shibata, Y., Hall, H., Greenleaf, A. L. & Strahl, B. D. (2005) A novel domain in Set2 mediates RNA polymerase II interaction and couples histone H3 K36 methylation with transcription elongation. Mol Cell Biol. 25:3305-3316.
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Xiao, T. Kao, C. F., Krogan, N., Sun, Z.-W., Greenblatt, J. F., Osley, M. A., & Strahl, B. D. (2005) Histone H2B ubiquitylation is associated with elongating RNA polymerase II. Mol Cell Biol. 25:637-651.
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Lee, D. Y., Teyssier, C., Strahl, B. D. & Stallcup, M. R. (2005) Role of Protein Methylation in Regulation of Transcription. Endocrine Reviews 26:147-170.
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Lee, C.-K., Shibata, Y., Rao, B., Strahl, B. D. & Lieb, J. D. (2004) Evidence for Nucleosome Depletion at Active Regulatory Regions Genomewide. Nature Genet., 36:900-905.
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Anest, V., Hanson J. L., Cogswell P. C., Steinbrecher K. A., Strahl B. D., & Baldwin A. S. (2003) A nucleosomal function for IkB kinase-b in NF-kB-dependent gene expression. Nature, 423:659-663.
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Xiao, T., Hall, H., Kizer, K. O., Shibata, Y., Hall, M. C., Borchers, C. H. & Strahl, B. D. (2003) Phosphorylation of RNA polymerase II CTD regulates H3 methylation in yeast. Genes & Dev. 17:654-663.
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Briggs, S. B., Xiao, T., Sun, Z.-W., Caldwell, J. A., Shabanowitz, J., Hunt, D. F., Allis, C. D. & Strahl, B. D. (2002) Trans-histone regulatory pathway in chromatin. Nature, 418:498.
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Briggs, SB & Strahl, BD (2002) Unraveling heterochromatin. Nat Genetics, 30:241-242.
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Li, J., Lin, Q., Yoon, H.-G., Strahl, B. D., Allis, C. D. & Wong, J. (2002) Involvement of histone methylation and phoshporylation in regulation of transcription by thyroid hormone receptor. Mol. Cell. Biol. 22:5688-5697.
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Strahl, B. D., Grant, P. A., Briggs, S. D., Bone J. R., Caldwell, J. A., Cook, R. G., Sun, Z.-W., Mollah, S., Shabanowitz, J., Hunt, D. F. & Allis, C. D. (2002) Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression. Mol. Cell. Biol. 22:1298-1306.
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Ma, H., Baumann, C. T., Li, H., Strahl, B.D., Rice, R., Jelinek, M. A., Aswad, D. W., Allis, C. D., Hager, G. L. & Stallcup, M. R. (2001) Hormone-dependent, CARM1-directed, arginine-specific methylation of histone H3 on the mouse mammary tumor virus promoter. Current Bio. 11:1981-1985.
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Bryk, M., Briggs, S. D., Strahl B. D., Curcio, M. J., Allis, C. D. & Winston F. (2002) Set1, a factor required for methylation of histone H3, regulates rDNA silencing in Saccaromyces cervisiae by a Sir2-independent mechanism. Current Bio. 12:165-170.
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Briggs, S. D., Bryk, M. Strahl, B. D., Cheung, W. L. Davie, J. K., Dent, Y. R. S., Winston, F. & Allis, C. D. (2001) Histone H3 lysine 4 methylation is mediated by Set1 and required for rDNA silencing in Saccharomyces cerevisiae. Genes and Dev. 15:3286-3295.
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Wang, H, Huang, Z. -Q., Xia, l., Feng, Q., Erdjument-Bromage, H., Strahl, B. D., Briggs, S. D. Allis C. D, Wong, J., Tempst, P. & Zhang, Y. (2001) Methylation of histone H4 at arginine 3 facilitates transcriptional activation by nuclear hormone receptor. Science 293:853-857.
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Strahl, B. D.*, Briggs, S. D.*, Brame, C. J., Caldwell, J. A. Koh, S., Ma, H., Cook, R. G., Shabanowitz, J., Hunt D. F., Stallcup, M. R. & Allis, C. D. (2001) Methylation of histone H4 at arginine 3 occurs in vivo and is mediated by the nuclear receptor coactivator PRMT1. Current Bio. 11:996-1000.
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Nakayama, J. -I., Rice J. C., Strahl, B. D., Allis, C. D. & Grewal, S. I. S. (2001) Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly. Science 292:110-113.
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Rea, S., Eisenhaber, F., O’Carroll, D., Strahl, B. D., Sun, Z-W, Opravil, S., Schmid, M., Mechtler, K., Ponting, C., Allis, C. D. & Jenuwein, T. (2000) Regulation of chromatin structure by site-specific histone H3 methyltransferases. Nature 406:593-599.
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Strahl, B. D. & Allis, C. D. (2000) The language of covalent histone modifications. Nature 403:41-45.
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Strahl, B. D., Ohba, R., Cook, R. G. & Allis, C. D. (1999) Methylation of histone H3 at lysine 4 is highly conserved and correlates with transcriptionally active nuclei in Tetrahymena. Proc. Natl. Acad. Sci. USA 96:14967-14972.
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Miller, W. L., Shafiee-Kermani, F., Strahl B. D., Huang, H. J. (2002) The Nature of FSH induction by GnRH. Trends Endocrinol. Metab. 6:257-263.
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Huang, H-J., Sebastian J., Strahl, B. D., Wu, J. C. & Miller, W. L. (2001) Transcriptional Regulation of the ovine FSH-beta gene by activin and GnRH: Involvement of two proximal AP-1 Sites for GnRH-Stimulation. Endocrinology 142:2267-2274.
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Huang, H-J., Sebastian J., Strahl, B. D., Wu, J. C. & Miller, W. L. (2001) The promoter for ovine follicle-stimulating hormone-ß gene (FSHß) confers FSHß-like expression on luciferase in transgenic mice: regulatory studies in vivo and in vitro. Endocrinology 142:2260-2266.
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Strahl, B. D., Huang, H.-J., Sebastian, J., Ghosh, B. R. & Miller, W. L. (1998) Transcriptional activation of the ovine follicle-stimulating hormone ß-subunit gene by GnRH: involvement of two AP-1-binding sites and protein kinase C. Endocrinology 139:4455-4465.
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Strahl, B. D., Huang, H.-J., Pederson, N. R., Wu, J. C., Gosh, B. R. & Miller, W.L. (1997) Two proximal AP-1-binding sites are sufficient to stimulate transcription of the ovine follicle-stimulating hormone-ß gene. Endocrinology 138:2621-2631.
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Ghosh, B. R., Wu, J. C., Strahl, B. D., Childs, G. V. & Miller, W. L. (1996) Inhibin and estradiol alter gonadotropes differentially in ovine pituitary cultures: changing gonadotrope numbers and calcium responses to gonadotropin-releasing hormone. Endocrinology 137:5144-5154.
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Strahl, B. D. & Lombardi, J. (1994) Microdetermination of dry mass content in the uterine fluid of four species of viviparous sharks (Squalus acanthias, Carcharhinus plumbeus, Mustelus canis and Rhizoprionodon terraenovae). Comp. Biochem. Physiol. 108A:213-219.